Xiaohui Fang Selected Research

Pulmonary Edema

11/2021	Delayed angiopoietin-2 blockade reduces influenza-induced lung injury and improves survival in mice.
1/2021	Inhibition of the lipoxin A4 and resolvin D1 receptor impairs host response to acute lung injury caused by pneumococcal pneumonia in mice.
1/2020	Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation.
11/2019	Clinically relevant model of pneumococcal pneumonia, ARDS, and nonpulmonary organ dysfunction in mice.
1/2018	Cigarette smoke exposure worsens acute lung injury in antibiotic-treated bacterial pneumonia in mice.
9/2017	Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice.
8/2015	Human Mesenchymal Stem (Stromal) Cells Promote the Resolution of Acute Lung Injury in Part through Lipoxin A4.
8/2010	Allogeneic human mesenchymal stem cells restore epithelial protein permeability in cultured human alveolar type II cells by secretion of angiopoietin-1.
9/2009	Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin-induced acute lung injury in the ex vivo perfused human lung.
8/2007	Acute lung injury edema fluid decreases net fluid transport across human alveolar epithelial type II cells.

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Xiaohui Fang Research Topics

Disease

16	Acute Lung Injury 11/2021 - 09/2003
14	Pulmonary Edema 11/2021 - 09/2003
13	Lung Injury 01/2022 - 01/2002
8	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 11/2021 - 09/2003
8	Edema (Dropsy) 12/2020 - 04/2002
7	Infections 02/2022 - 04/2007
5	Inflammation (Inflammations) 01/2022 - 11/2003
5	Sepsis (Septicemia) 01/2022 - 04/2002
3	Pneumonia (Pneumonitis) 11/2019 - 11/2003
2	Human Influenza (Influenza) 11/2021 - 03/2016
2	Bacterial Pneumonia 11/2019 - 01/2018
2	Lung Diseases (Lung Disease) 11/2019 - 03/2016
1	Disease Progression 02/2022
1	Lung Neoplasms (Lung Cancer) 01/2022
1	Virus Diseases (Viral Diseases) 01/2022
1	Systemic Inflammatory Response Syndrome (Sepsis Syndrome) 01/2021
1	Neoplasms (Cancer) 01/2021
1	Animal Disease Models 01/2021
1	Ovarian Neoplasms (Ovarian Cancer) 01/2021
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021
1	Pneumococcal Pneumonia 01/2021
1	Femoral Neck Fractures 11/2020
1	Systemic Lupus Erythematosus (Libman-Sacks Disease) 11/2020
1	Autoimmune Hepatitis 11/2020
1	Rheumatoid Arthritis 11/2020
1	Autoimmune Diseases (Autoimmune Disease) 11/2020
1	Vesicular Stomatitis 01/2019
1	Influenza in Birds (Avian Flu) 03/2016
1	Critical Illness (Critically Ill) 01/2014
1	Wounds and Injuries (Trauma) 01/2013
1	Idiopathic Pulmonary Fibrosis 07/2011
1	Ischemia 06/2008
1	Cysts 05/2007
1	Thrombosis (Thrombus) 10/2005
1	Pulmonary Infarction 10/2005
1	Hypoxia (Hypoxemia) 10/2005

Drug/Important Bio-Agent (IBA)

9	Proteins (Proteins, Gene)FDA Link 11/2021 - 11/2003
8	CytokinesIBA 02/2022 - 11/2003
4	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2018
3	EndotoxinsIBA 01/2022 - 09/2009
3	Biomarkers (Surrogate Marker)IBA 01/2022 - 09/2017
3	SodiumIBA 08/2007 - 11/2003
2	VaccinesIBA 02/2022 - 01/2022
2	Acetates (Acetic Acid Esters)FDA Link 01/2022 - 12/2020
2	AerosolsIBA 01/2022 - 12/2020
2	Biological ProductsIBA 01/2022 - 01/2022
2	Vitamin E FDA LinkGeneric 01/2022 - 12/2020
2	Nicotine FDA Link 01/2022 - 08/2007
2	Peptides (Polypeptides)IBA 11/2021 - 01/2021
2	lipoxin A4IBA 01/2021 - 08/2015
2	SmokeIBA 01/2018 - 09/2017
2	ChloridesIBA 08/2007 - 01/2005
2	AcidsIBA 08/2007 - 07/2004
2	Protein CIBA 09/2003 - 04/2002
1	Angiopoietin-2IBA 11/2021
1	Angiopoietin-1IBA 11/2021
1	RNA (Ribonucleic Acid)IBA 11/2021
1	Glycoproteins (Glycoprotein)IBA 01/2021
1	olfactomedinIBA 01/2021
1	Long Noncoding RNAIBA 01/2021
1	MicroRNAs (MicroRNA)IBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Messenger RNA (mRNA)IBA 01/2021
1	Formyl Peptide Receptors (Formyl Peptide Receptor)IBA 01/2021
1	resolvin D1IBA 01/2021
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2021
1	OilsIBA 12/2020
1	Programmed Cell Death 1 Ligand 2 ProteinIBA 11/2020
1	LigandsIBA 11/2020
1	AS 35IBA 11/2019
1	Ferritins (Ferritin)IBA 01/2019
1	enhanced green fluorescent proteinIBA 01/2019
1	ChemokinesIBA 01/2018
1	Interleukin-6 (Interleukin 6)IBA 09/2017
1	LipidsIBA 08/2015
1	HMGB1 Protein (HMG1)IBA 01/2013
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 01/2013
1	Neutralizing AntibodiesIBA 12/2010
1	Conditioned Culture MediaIBA 09/2009
1	salicylhydroxamic acid (SHAM)IBA 06/2008
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2008
1	ProteomeIBA 06/2008
1	4- (4- fluorophenyl)- 2- (4- hydroxyphenyl)- 5- (4- pyridyl)imidazoleIBA 08/2007
1	p38 Mitogen-Activated Protein KinasesIBA 08/2007
1	Receptor for Advanced Glycation End ProductsIBA 08/2007
1	Choline (Choline Chloride)IBA 08/2007
1	alpha7 Nicotinic Acetylcholine ReceptorIBA 08/2007
1	Integrin beta1IBA 05/2007
1	Surface-Active Agents (Surfactants)IBA 05/2007
1	ColforsinIBA 05/2007
1	Endothelial Protein C ReceptorIBA 04/2007
1	FibrinIBA 04/2007
1	Adrenergic Agonists (Adrenergic Receptor Agonist)IBA 07/2004
1	Adenosine Monophosphate (AMP)IBA 07/2004
1	Salmeterol Xinafoate (Serevent)FDA Link 07/2004

Therapy/Procedure

6	Therapeutics 01/2020 - 04/2002
1	Operative Surgical Procedures 11/2020
1	Resuscitation 11/2019
1	Drug Therapy (Chemotherapy) 01/2015
1	Transplantation 10/2005